Wan Syaheedah Wan Ghazali
Universiti Sains Malaysia, MalaysiaPresentation Title:
Home-based circuit training improves cardiovascular parameters, glycemic control, pain levels, and health-related quality of life in overweight/obese older adults with knee osteoarthritis and type 2 diabetes: A randomized controlled trial during the COVID-19 pandemic
Abstract
Background: There is substantial evidence linking obesity, type 2 diabetes mellitus (T2DM), and knee osteoarthritis (KOA). Regular exercise is a critical component of preventive therapy for KOA, yet there is a paucity of evidence-based exercise protocols for individuals with comorbid obesity, T2DM, and KOA. This trial aimed to assess the effectiveness of a 12-week home-based circuit training (HBCT) protocol on cardiovascular parameters, glycemic control, pain levels, and health-related quality of life (HRQoL) in overweight/obese older adults with KOA and T2DM during the COVID-19 lockdown.
Methods: Seventy overweight/obese patients with KOA and T2DM (mean age 62.2 ± 6.1 years; 56% female) were randomly assigned to either the intervention group (n=35, HBCT) or the no-exercise control group (n=35, CON). The HBCT group followed a 12-week progressive protocol comprising seven exercises, with 15–30 repetitions per exercise, 1 minute of passive rest between exercises, and 2–4 rounds per session, lasting 20–60 minutes per session. Cardiovascular parameters were evaluated, and blood samples were collected to measure lipid profile, HbA1c, and fasting blood glucose (FBG). Pain levels were assessed using the Visual Analog Scale, and HRQoL was measured using the Osteoarthritis Knee and Hip Quality of Life questionnaire. Assessments were conducted at pre, mid-, and post-training stages.
Results: The HBCT group exhibited significant reductions in blood pressure, body mass index, total cholesterol, triglycerides, low-density lipoprotein cholesterol, HbA1c, FBG, and knee pain (p < 0.05). Additionally, there were significant increases in high-density lipoprotein cholesterol and HRQoL (p < 0.05).
Conclusion: The findings suggest that an HBCT program can improve cardiovascular health, glycemic control, pain levels, and HRQoL in elderly individuals with overweight/obesity, T2DM, and KOA. These results offer valuable insights for clinicians and practitioners seeking evidence-based exercise interventions tailored to this patient population in clinical practice.
Biography
Wan Syaheedah Wan Ghazali graduated with a Bachelor of Medicine, Bachelor of Surgery (MBBS), and MSc in Medical Physiology. She completed her PhD at the University of Nottingham, United Kingdom. She is a senior lecturer in the Physiology Department at Universiti Sains Malaysia, Malaysia Her research areas include Cardiovascular Physiology, Obesity, and Alternative & Complementary Medicine.
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